Phytochemical composition of the essential oil, total phenolic content and antioxidant activity in Salvia mirzayanii Rech. & Esfand. grown wild and cultivated in Iran

Salvia mirzayanii is member of Lamiaceae family, which distributes only in south of Iran. Phytochemical composition of essential oil isolated by hydro distillation from the aerial parts of Salvia mirzayanii Rech. & Esfand. grown wild and cultivated in Iran were determined using Gas Chromatography (GC) and Gas Chromatography/Mass Spectrometry (GC/MS). Forty nine components were identified in the essential oil of wild S. mirzayanii. The major components were, 5neo-cedranol (15.48%), 1,8-cineol (11.23%), α-terpinyl acetate (9.64%), γ-cadinene (6.64%), bicyclogermacrene (6.47%), -cadinene (5.46%), Globulol (5.12%), α -cadinol (4.58%), epi-α-Cadinol (4.20%), Linalool (3.35%), 7-epiα-selinene (3.23%), Linalyl acetate (2.55%) and α -guaiene (2.23%). Seventy two components were identified in the essential oil of cultivated S. mirzayanii. The major components in cultivated S. mirzayanii were, 5-neo-cedranol (19.42%), spathulenol (7%), αterpinyl acetate (6.70%), Linalool (6.64%), 1,8-cineol (6.28%), 7-epiα-selinene (5.46%), α -cadinol (3.73%), (Z)-Nerolidol (3.34%), epi-α-Cadinol (2.59%), -cadinene (2.58%), Linalyl acetate (2.54%), camphor (2.42%), globulol (2.36%), bicyclogermacrene (2.05%) and carvacrol (2.03%). The total phenolic content and the antioxidant activity of plant extract was determined by Folin-Ciocalteau and the 2,2-diphenyl-1-picrylhydrazyl (DPPH) free radical scavenging assays respectively. The highest total phenolic content and antioxidant activities were observed in cultivated S. mirzayanii compare wild growing plants.